Drug Discovery by Formulation Design and Innovative Drug Delivery Systems (DDS)

Novel transdermal drug delivery systems

Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...

Microsponges as Innovative Drug Delivery Systems

Transdermal drug delivery system (TDDS) is not practicable for delivery of materials whose final target is skin itself. Controlled release of drugs onto the epidermis with assurance that the drug remains primarily localized and does not enter the systemic circulation in significant amounts is a challenging area of research. Microsponges are highly porous micro-sized particles with a unique abil...

Formulation Design and Development of Self-Nanoemulsifying Drug Delivery Systems Containing a Hydrophobic Selective β1-Adrenoreceptor Blocker

The present work was aimed to design and develop self-nanoemulsifying drug delivery systems (SNEDDS) with the objective to overcome the problems associated with the delivery of talinolol, a hydrophobic and poorly bioavailable drugs having pH dependant solubility. The solubility of talinolol in various oils, surfactants, cosurfactants and aqueous phases were determined to identify and select the...

Ethnobotany, Ethnopharmacology and Drug Discovery

     This manuscript is a review of a number of ethnobotany and ethnopharmacology texts and papers in order to arrive at current understanding and scope of ethnobotany and ethnopharmacology. It includes either a brief definition of both fields and presenting some examples on them. Also it has a glimpse on the geographical coverage of research works throughout the world, important issue of prope...

trends in design and evaluation of drug delivery systems